MCCTTool

Introduction

No two instruments are identical. Data generated from different instruments can rarely be used with the same model. It may be prohibitively expensive or otherwise impossible to run an entire complement of calibration samples on new instrument. A calibration transfer step can be developed to transform "slave" instrument data to look like it came from a "master" instrument.

Modelcentric Calibration Transfer (MCCT) refers to the situation where a model has been developed on a "master" instrument and is the basis of creating a "slave" model that includes a calibration transfer step in the preprocessing structure. It is assumed there data sets for both instruments with matched samples. How data is preprocessed can affect the standardization. The location of calibrations transfer step within the preprocessing can have a large impact on how well the slave model will perform. The MCCT Tool allows the testing of different combinations of calibrations transfer methods and parameters, and where the calibration transfer step is inserted into the preprocessing.